Plasticity (neuroplasticity)

Plasticity refers to the nervous system’s ability to adapt and reorganize.

While this is essential for recovery and learning, it can also reinforce pain pathways when pain persists. In chronic pain, plastic changes in the spinal cord and brain can maintain sensitivity even after tissues heal. Harnessing plasticity in a positive way — through rehabilitation, cognitive-behavioral therapy, graded activity or neuromodulation — is central to modern pain management.