Migraine is a neurological disorder characterized by recurrent headaches, often accompanied by nausea, sensitivity to light and sound, and sometimes visual disturbances (aura).
It is thought to result from abnormal brain excitability, involving both vascular changes and neuroinflammation. Migraines can be disabling and affect quality of life significantly. Treatment ranges from lifestyle management and preventive medications to targeted therapies like CGRP antagonists. Understanding migraine has also helped shape broader concepts of central sensitization in chronic pain.