Antinociception

Antinociception is the process of blocking or dampening the body’s detection of painful stimuli.

It can occur naturally through the body’s own pain-control systems (like endorphins) or can be induced by medical treatments. Techniques such as pulsed radiofrequency, spinal cord stimulation, or certain medications work by enhancing antinociceptive pathways. Understanding antinociception helps physicians design treatments that don’t just mask pain, but actively modify how the nervous system responds to it.